The label shows how strong the evidence is, not how big the effect is. Tap a claim to see its papers.
In plain words
There is no measured effect of raspberry ketone alone in people. In a blend with caffeine and other stimulants, one industry-sponsored trial reported -2.0% vs -0.5% body weight over 8 weeks; in another, weight and fat losses were reported for both groups together, with supplement-only effects limited to lean mass in men, hip girth in women and adipokines.[2][3]
No human trial of raspberry ketone alone exists. Two 8-week trials of stimulant blends containing it gave conflicting results, one industry-sponsored.[1][2][3][4]
All efficacy claims rest on cell and rodent studies. The two human RCTs tested blends with caffeine, capsaicin and Citrus aurantium, so any effect cannot be attributed to raspberry ketone. No direct human support, so Grade D.
Each plate is one paper. Taller = stronger study design, wider = more studies pooled. Tap one.
Raspberry ketone is an aroma compound from red fruits used as a weight-loss product; its weight effect is controversial, partly because animal results may reflect lower food intake.
Raspberry ketone effects come from cell and rodent studies; despite a lack of reliable human research it is marketed at very high doses.
In 36 overweight adults on diet and exercise for 8 weeks, a raspberry ketone, capsaicin, caffeine, garlic and Citrus aurantium supplement led to weight and fat loss reported for both groups; supplement-only effects were lean mass in men, hip girth in women, and leptin/adiponectin.
In 70 obese adults (45 completers) on diet and exercise, an 8-week multi-ingredient product containing raspberry ketone, caffeine, capsaicin, garlic, ginger and Citrus aurantium reduced weight and fat more than placebo. Sponsored by the product maker.
Raspberry ketone (4-(4-hydroxyphenyl)-2-butanone) is the aroma compound that gives red raspberries their smell; it also occurs in kiwifruit, peaches and apples. Raspberries contain up to 4.3 mg/kg, so supplement doses of 100-1400 mg/day are far beyond what food provides (Bredsdorff 2015).
In cells and rodents raspberry ketone activates PPAR-alpha and is proposed to increase fat breakdown and fat oxidation. Some animal results may simply reflect lower food intake. None of these mechanisms has been shown in humans.[1][4]
Reviewed 03 Oct 2026 · every PubMed ID checked against PubMed
Products recommend 100-1400 mg/day; no human dose-finding exists
Never tested in a human RCT.[1]
| Food | Amount |
|---|---|
| Red raspberries | Up to 4.3 mg/kg[5] |
Raspberry ketones are clinically proven to burn fat
Evidence comes from cell and rodent studies; no human trial has tested raspberry ketone alone.[1]
It is just a fruit extract, so it must be safe
Supplement doses far exceed food amounts and toxicity data exist only from short rat studies.[5]
Find a supplement or a page
